PKRRATING CAN BE FUN FOR ANYONE

The interfacial residues are really conserved among eIF2α kinases and mutagenesis implicates the BTB dimer in PKR function18. FRET measurements display that the kinase domains dimerize when PKR binds to activating dsRNAs19. These observations guidance a product where by activating RNA serves as a scaffold to bind various PKR monomers, raising the

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